Unsubstituted Phenols
Medchemexpress LLC HY-113093 5mg Medchemexpress, Ethyl glucuronide CAS:17685-04-0 Purity:>98%
Medchemexpress, HY-113093 5mg Ethyl glucuronide CAS:17685-04-0 Ethyl glucuronide is an endogenous metabolite. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
eMolecules 555-66-8 | Medchem Express | Shogaol | 5mg | 446264383 | HY-14616 | MFCD01736094 | 276.376 | C17H24O3
Medchem Express | Shogaol | 5mg | 446264383 | HY-14616 | 555-66-8 | MFCD01736094 | 276.376 | C17H24O3
Medchemexpress LLC Diosmetin 7-o-beta-d-glucuronide | 35110-20-4 | 10 MG
Diosmetin 7-o-beta-d-glucuronide is an antioxidant constituent found in the fruits of Luffa cylindrical.
- Product type: Natural products
- Targets others
eMolecules 69839-83-4 | Medchem Express | Didox | 5mg | 446269827 | HY-19387 | MFCD01667810 | 169.136 | C7H7NO4
Medchem Express | Didox | 5mg | 446269827 | HY-19387 | 69839-83-4 | MFCD01667810 | 169.136 | C7H7NO4
Medchemexpress LLC 5-benzyl-2-hydroxy-3-nitrobenzaldehyde | 328565-16-8 | MFCD00852947 | 99.9% | 257.24 g·mol⁻¹ | C14H11NO4 | 50MG
Col003 (5-benzyl-2-hydroxy-3-nitrobenzaldehyde) is a selective small-molecule inhibitor of heat shock protein 47 (Hsp47) that competitively binds the collagen-binding site. It has a reported IC50 of 1.8 μM and is supplied as a high-purity research reagent for in vitro studies of collagen secretion and fibrosis-related pathways.
- Selective Hsp47 inhibition (IC50 = 1.8 μM).
- High purity suitable for biochemical assays (99.87%).
- Molecular formula C14H11NO4, molecular weight 257.24 g·mol⁻¹.
- Available in small pack sizes for research use, including 50 mg.
- Used to investigate collagen secretion and fibrosis-related mechanisms.
Medchemexpress LLC 3,4-dihydroxymandelic acid | 775-01-9 | MFCD00004231 | >98.0% | 184.15 | C8H8O5 | 5 MG
3,4-Dihydroxymandelic acid is an endogenous metabolite of norepinephrine commonly used as an analytical standard in biochemical and metabolic studies. Supplied as a high-purity solid, it is appropriate for method development, calibration, and quantification of catecholamine metabolites in biological samples.
- Used as an analytical standard for quantification of norepinephrine metabolites.
- High purity (≥98.0%) supports accurate analytic results.
- Chemical formula C8H8O5; molecular weight 184.15 g/mol.
- White to off-white solid suitable for preparation of standards and controls.
- Stable under frozen storage to preserve integrity for analytical use.
eMolecules 62949-77-3 | Medchem Express | Kuwanon A | 2mg | 415689166 | HY-N2300 | MFCD31382182 | 420.461 | C25H24O6
Medchem Express | Kuwanon A | 2mg | 415689166 | HY-N2300 | 62949-77-3 | MFCD31382182 | 420.461 | C25H24O6
Medchemexpress LLC Kuwanon E | 68401-05-8 | 1 MG
Kuwanon E is a flavonoid isolated from *Morus alba*. It exhibits cytotoxicity to human monocytic leukemic cell lines and reduces the level of IL-1β. This compound demonstrates cytotoxic activity against the THP-1 human monocytic leukemic cell line with an IC50 of 4.0 ± 0.08 μM.
- Isolated from *Morus alba*
- Cytotoxic to human monocytic leukemic cell lines
- Reduces the level of IL-1β
- Inhibits SERCA1 in New Zealand rabbit skeletal muscle SR vesicles
- For research use only
Medchemexpress LLC HY-18980 10mg Medchemexpress, Rottlerin CAS:82-08-6 Purity:>98%
Medchemexpress, HY-18980 10mg Rottlerin CAS:82-08-6 Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC 50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM. Rottlerin acts as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1. Rottlerin induces apoptosis via caspase 3 activation [1] [2] [3] . Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Ko 143 | 461054-93-3 | MFCD19053160 | 100.0% | 469.6 g/mol | C26H35N3O5 | 1 ML
Potent, selective ABCG2 (BCRP) inhibitor used to probe transporter function and multidrug resistance. Shows over 200-fold selectivity versus P-gp and MRP-1; supplied as a 10 mM solution in 1 mL for laboratory use.
- Potent and selective ABCG2 (BCRP) inhibitor for transporter studies.
- Displays greater than 200-fold selectivity over P-gp and MRP-1.
- Supplied as a 10 mM solution in 1 mL for convenient dosing.
- Molecular weight 469.6 g/mol and formula C26H35N3O5.
- CAS number 461054-93-3 for unambiguous identification.
eMolecules 257930-74-8 | Medchem Express | Secoisolariciresinol diglucoside | 5mg | 446258754 | HY-105008 | 686.704 | C32H46O16
Medchem Express | PD 407824 | 5mg | 515744293 | HY-18961 | 622864-54-4 | MFCD09753286 | 328.327 | C20H12N2O3
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Medchemexpress LLC Navarixin | 473727-83-2 | 99.3% | 397.42 g/mol | C21H23N3O5 | 10 MG
Navarixin is an orally active, allosteric antagonist of CXCR1 and CXCR2 used as a research compound to study chemokine receptor signaling, neutrophil recruitment, and inflammatory responses in vitro and in vivo.
- Potent, allosteric antagonist of CXCR1 and CXCR2.
- Suitable for in vitro and in vivo pharmacology studies.
- High purity (99.3%) for consistent experimental results.
- Soluble in DMSO at ≥50 mg/mL; several in vivo vehicle formulations reported.
- Recommended storage supports long-term stability of powder and solutions.
- Available in small research quantities for dosing flexibility.
Medchemexpress LLC HY-112104 50mg Medchemexpress, Meta-Topolin CAS:75737-38-1 Purity:>98%
Medchemexpress, HY-112104 50mg Meta-Topolin CAS:75737-38-1 Meta-Topolin (m-Topolin) is a highly active aromatic cytokinin. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Ko 143 461054-93-3 25mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Medchemexpress LLC Isosilybin B | 142796-22-3 | 1 MG
Isosilybin B is a flavonolignan isolated from Silybum marianum that demonstrates anticancer activity, particularly against prostate cancer. Its mechanisms involve regulating cell cycle proteins and promoting apoptosis.
- Regulates cell cycle-related proteins (cyclins, Cdk4, Cdk2, Cdc25A).
- Activates caspases (caspase-9 and caspase-3) to promote apoptosis.
- Reduces androgen receptor (AR) and prostate-specific antigen (PSA) levels.
- Exhibits cytotoxicity in Huh-7 cells with an IC50 of 27 μM.
- Induces G1 arrest and increased cell death in LNCaP and 22Rv1 prostate cancer cells.