Unsubstituted Phenols
Apexbio Technology LLC Phenol Red sodium salt 34487-61-1 5g
Phenol Red sodium salt (34487-61-1) is a small molecule compound binding to estrogen receptors It can interact with estrogen receptors thereby modulating downstream signaling pathways and associated cellular processes Phenol Red sodium salt functions primarily via estrogen receptor affinity In cell-based studies it binds to estrogen receptors in human breast cancer cell lines such as MCF-7 cells Based on these properties Phenol Red sodium salt holds research potential in oncology studies particularly those investigating hormone-mediated signaling pathways and receptor-mediated cellular responses
Apexbio Technology LLC Ko 143 461054-93-3 25mg
Ko 143 (CAS 461054-93-3) is a selective inhibitor of the breast cancer resistance protein (BCRP/ABCG2) an ATP-binding cassette transporter implicated in multidrug resistance in cancer cells By targeting BCRP Ko 143 effectively blocks BCRP-mediated drug efflux as demonstrated by an EC90 of 26 nM in cell-based assays This compound exhibits over 200-fold selectivity for BCRP compared to P-glycoprotein and MRP1 In vitro Ko 143 reverses BCRP-mediated resistance to chemotherapeutics such as topotecan and mitoxantrone enhancing their potency up to tenfold in relevant cancer cell lines Ko 143 has been used in murine models to increase systemic exposure of BCRP substrates supporting its utility in studying drug resistance mechanisms and improving chemotherapeutic efficacy in preclinical research
Medchemexpress LLC Raspberry ketone glucoside (Standard) | 38963-94-9 | 100 MG
Raspberry ketone glucoside (Standard) is an analytical standard that acts as a melanogenesis inhibitor. It functions by activating the IL6/JAK1/STAT3 pathway, which inhibits the transcriptional activity of MITFa and downstream expression of TYR and TYRP1a genes. This compound has shown significant whitening activity both in vitro on B16F10 cells and in vivo in a zebrafish model. It is suitable for qualitative, quantitative, and methodological research experiments like HPLC, GC, and MS.
- Acts as a melanogenesis inhibitor
- Activates the IL6/JAK1/STAT3 pathway
- Inhibits transcriptional activity of MITFa and expression levels of TYR and TYRP1a genes
- Demonstrates significant whitening activity on B16F10 cells in vitro and in a zebrafish model in vivo
- Functions as an analytical standard for assays
- Suitable for qualitative, quantitative, and methodological research experiments (HPLC, GC, MS)
![Medchemexpress LLC N-[5-amino-1,2,3,4-tetrahydro-1-[4-(trifluoromethyl)phenyl]-3-quinolinyl]-2-propenamide | 2766575-48-6 | MFCD22417285 | 99.8% | 361.36 | C19H18F3N3O | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285876.png-250.jpg)
Medchemexpress LLC N-[5-amino-1,2,3,4-tetrahydro-1-[4-(trifluoromethyl)phenyl]-3-quinolinyl]-2-propenamide | 2766575-48-6 | MFCD22417285 | 99.8% | 361.36 | C19H18F3N3O | 10 MG
SWTX-143 is a covalent, irreversible inhibitor of the YAP/TAZ-TEAD transcriptional complex developed for research. It binds the palmitoylation pocket of TEAD isoforms and suppresses YAP/TAZ-TEAD transcriptional activity, and has demonstrated oral activity in preclinical studies. The compound is supplied as a high-purity solid intended for biochemical and cell-based research applications.
- Covalent, irreversible inhibitor of YAP/TAZ-TEAD.
- Binds the palmitoylation pocket of TEAD isoforms.
- Inhibits YAP/TAZ-TEAD transcriptional activity.
- Demonstrated oral activity in preclinical studies.
- High reported purity (about 99.8%).
- Supplied as a white to off-white solid.
- Available in milligram-scale packages for laboratory research.
- Suitable for biochemical and cell-based assays.
Medchemexpress LLC 2-amino-2',5-dichlorobenzophenone | 2958-36-3 | 99.95% | 266.12 | 25 G
(2-Amino-5-chlorophenyl)(2-chlorophenyl)methanone is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is for research use only and not sold to patients.
- Can be used as a biological material
- Can be used as an organic compound for life science related research
- For research use only
Sigma Aldrich Fine Chemicals Biosciences NS 1619 powder | 153587-01-0 | MFCD00928190 | 25MG
NS 1619 powder | Mol Wt: 362.23 | 153587-01-0 | MFCD00928190 | 25MG
Medchemexpress LLC Phenol red | 143-74-8 | 98.0% | 25 G
Phenol red (Phenolsulfonephthalein) is a pH indicator dye that displays a distinct color change from pink to yellow in the event of a positive reaction. It is commonly used as a standard pH indicator in various cell and tissue culture media to quickly check the health of the culture. Additionally, it has been utilized in protocols for detecting cellular hydrogen peroxide and peroxidase activity from human peroxidase enzymes.
- pH indicator dye
- Color change from pink to yellow
- Used in cell and tissue culture media
- Can detect cellular hydrogen peroxide and peroxidase activity
- Solid appearance, red to reddish brown color
- For research use only
Medchemexpress LLC HY-N1504 5mg Medchemexpress, Loureirin B CAS:119425-90-0 Purity:>98%
Medchemexpress, HY-N1504 5mg Loureirin B CAS:119425-90-0 Loureirin B, a flavonoid extracted from Dracaena cochinchinensis , is an inhibitor of plasminogen activator inhibitor-1 (PAI-1) , with an IC 50 of 26.10 μM; Loureirin B also inhibits K ATP , the phosphorylation of ERK and JNK , and has anti-diabetic activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC 5-benzyl-2-hydroxy-3-nitrobenzaldehyde | 328565-16-8 | MFCD00852947 | 99.9% | 257.24 g·mol⁻¹ | C14H11NO4 | 50MG
Col003 (5-benzyl-2-hydroxy-3-nitrobenzaldehyde) is a selective small-molecule inhibitor of heat shock protein 47 (Hsp47) that competitively binds the collagen-binding site. It has a reported IC50 of 1.8 μM and is supplied as a high-purity research reagent for in vitro studies of collagen secretion and fibrosis-related pathways.
- Selective Hsp47 inhibition (IC50 = 1.8 μM).
- High purity suitable for biochemical assays (99.87%).
- Molecular formula C14H11NO4, molecular weight 257.24 g·mol⁻¹.
- Available in small pack sizes for research use, including 50 mg.
- Used to investigate collagen secretion and fibrosis-related mechanisms.
eMolecules Medchem Express / SYP-5 / 5mg / 446255902 / HY-100693 / / 1384268-04-5 / MFCD30534394 / 312.380 / C18H16O3S
Medchem Express / SYP-5 / 5mg / 446255902 / HY-100693 / / 1384268-04-5 / MFCD30534394 / 312.380 / C18H16O3S
eMolecules BENZYL (3-HYDROXYBENZYL)CARBAMATE | 75383-61-8 | MFCD14585006 | 1g
AstaTech | BENZYL (3-HYDROXYBENZYL)CARBAMATE | 1g | 451913878 | S10323 | 95.000 | 75383-61-8 | MFCD14585006 | 257.289 | C15H15NO3
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ILEX LIFE SCIENCES LLC TRYPSIN/EDTA P10-019100 100ML
PAN-Biotech Trypsin 0.25% / EDTA 0.02% in DPBS, w/o: Ca and Mg, w: Phenol red (100 ml). DESCRIPTION: PAN-Biotech Trypsin 0.25% / EDTA 0.02% in PBS, w/o: Ca and Mg, w: Phenol Red is a porcine pancreas-derived enzyme plus EDTA in a PBS solution. Trypsin-EDTA solution is commonly used for the dissociation of anchorage-dependent (adherent) mammalian cells and tissues from culture surfaces. The concentration of trypsin necessary to dislodge cells from their substrate is dependent on the cell type and the age of the culture. Ethylenediaminetetraacetic acid (EDTA), a chelating agent, is often added to trypsin solutions to enhance enzymatic activity by neutralizing calcium and magnesium ions that enhance cell-to-cell adhesion and obscure the peptide bonds on which trypsin acts. LIQUID/POWDER: Liquid. PHENOL RED: With Phenol Red. Ca/Mg CONTENT: Without Ca and Mg. TRYPSIN: 0.25% Trypsin. EDTA: 0.02% EDTA. STERILE: Yes. STORAGE TEMP.: -20°C. MANUFACTURER: PAN-Biotech GmbH (Germany).
Medchemexpress LLC HY-N0006 5mg Medchemexpress, Demethoxycurcumin CAS:22608-11-3 Purity:>98%
Medchemexpress, HY-N0006 5mg Demethoxycurcumin CAS:22608-11-3 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Temoporfin >=90% (HPLC) | 122341-38-2 | 5MG
Temoporfin >=90% (HPLC) | Purity: >=90% (HPLC) | Mol Wt: 680.75 | 122341-38-2 | 5MG
eMolecules Medchem Express / Isoquercitrin / 10mg / 446275352 / HY-N0768 / / 21637-25-2 / MFCD29050128 / 464.379 / C21H20O12
Medchem Express / Isoquercitrin / 10mg / 446275352 / HY-N0768 / / 21637-25-2 / MFCD29050128 / 464.379 / C21H20O12